ABSTRACT
To evaluate the frequency of hyponatremia and its prognostic importance in ST elevation myocardial infarction. Six months. Case series. Tertiary care hospital Hyderabad. All the cases with ST elevation myocardial infarction admitted in the CCU were recruited and evaluate for serum sodium level at admission and then at 24, 48 and 72 hours. The data was analyzed in SPSS 16 and the frequency and percentage was calculated. One hundred patients with acute myocardial infarction were recruited and assessed for sodium level. The mean age +/- SD of whole population was 57.52 +/- 9.51 whereas in male and female population it was 58.72 +/- 7.53 and 53.84 +/- 7.93 respectively. The sodium level was 130.21 +/- 3.42 and 127.41 +/- 4.21 in male and female population. The p-value was statistically significant [<0.01] in context to age and sex whereas the age in context to hyponatremia is non significant [p=0.77]. The hyponatremia and its severity was statistically significant in context to sex [p=0.04] and duration of the myocardial infarction [p=0.03]. The serum sodium level in context to duration of MI was also significant [p=0.03] whereas the mortality at the end of 30 days was 11% of which 02 patients had normal sodium level while the 09 had low sodium level [hyponatremia]. Hyponatremia in patients with acute STEMI is a important predictor of thirty days mortality
ABSTRACT
Objectives: to determine the frequency of hyperuricemia in patients with essential hypertension
Study Design: cross sectional descriptive
Period: six months study
Setting: liaquat University Hospital Hyderabad
Patients and Methods: all the patients with essential hypertension visited at cardiac OPD / admitted in the ward were further evaluated for serum uric acid level. The data was analyzed in SPSS 16 and the frequency and percentage was calculated
Results: during six months study period, total one hundred and eighty [180] patients with essential hypertension were recruited and study for uric acid level. The mean age +/- SD for overall population was 52.84 +/- 8.72 whereas it was 55.83 +/- 7.93 and 50.75 +/- 8.95 in male and female population respectively. The mean +/- SD of systolic and diastolic blood pressure [mmHg] in overall population was 160.50 +/- 12.74 and 100.70 +/- 5.95 respectively. The mean +/- SD serum uric acid level in overall population was 13.74 +/- 4.83 while it was 11.74 +/- 6.44 and 14.43 +/- 4.31 in male and female population respectively]. The male population was predominant in relation to age [p=0.02], the hyperuricemia was identified in 117/180 [65%] patients and it is statistically significant in context to age [p<0.01] and gender [p<0.05] whereas mean +/- SD of systolic and diastolic blood pressure was also significant in relation to hyperuricemia
Conclusion: there is a relationship between hyperuricemia and hypertension and shown that the serum uric acid level was significantly increased in patients with essential hypertension